Protein Purification Reagents and Kits
Genscript Corporation CD34 His Mouse
CD34 is a transmembrane phosphoglycoprotein first identified on hematopoietic stem and progenitor cells Clinically it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants Due to these historical and clinical associations CD34 expression is almost ubiquitously related to hematopoietic cells and it is a common misconception that CD34-positive (CD34()) cells in nonhematopoietic samples represent hematopoietic contamination
Antibodies Online TXNDC12 Protein (His tag) Recombinant Human Cells, This TXNDC12 protein is labelled with His tag. 50 μg
Background: Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain.
Genscript Corporation High Affinity Ni-Charged Resin
GenScript High Affinity Ni-Charged Resin FF is an 6% highly cross-linked agarose medium covalently coupled to a chelating agent that binds Ni2 by four coordination sites for high-affinity purification of polyhistidine-tagged recombinant proteins
eMolecules 2417370-39-7 | Medchem Express | PROTAC BRD4 degrader for PAC-1 | 1mg | 527574178 | HY-129938 | 1306.59 | C62H77F2N9O12S4
ChemScene | 23-Bipyridine | 1g | 794524402 | CS-W019058 | 581-50-0 | MFCD00006215 | 156.188 | C10H8N2
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AdipoGen CD152 hrecHis
Recombinant Protein. Human CD152 aa 36-161 is fused at the C-terminus to a His-tag. Source W2. Lyophilized. Contains PBS. CD152 Cytotoxic T-lymphocyte-associated protein 4 CTLA-4 is an inhibitory receptor belonging to the CD28 immunoglobulin subfamily, expressed primarily by T-cells. Its ligands, CD80 and CD86, are typically found on the surface of antigen-presenting cells and can either bind CD28 or CTLA-4, resulting in a costimulatory or a co-inhibitory response, respectively. Because of its dampening effect, CTLA-4 is a crucial regulator of T-cell homeostasis and self-tolerance. While CD28 promotes T-cell activation and proliferation, CTLA-4 is reported to dampen T-cell responses through a variety of mechanisms. Prior to activation, conventional T-cells Tconv express low levels of CTLA-4, predominantly in intracellular compartments. Upon activation, CTLA-4 expression is upregulated and becomes increasingly detectable on the cell surface.
eMolecules 83741-35-9 | ChemScene | 4-Bromo-1H-benzoimidazole | 1g | 536846585 | CS-W004724 | MFCD11973696 | 197.035 | C7H5BrN2
ChemScene | 4-Bromo-1H-benzoimidazole | 1g | 536846585 | CS-W004724 | 83741-35-9 | MFCD11973696 | 197.035 | C7H5BrN2
Genscript Corporation CD4/LEU3 His Mouse
CD4 also known as L3T4 T4 and W3/25 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes It is a standard phenotype marker for the identification of T cell populations Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses In T-cells functions primarily as a coreceptor for MHC class II molecule peptide complex
Genscript Corporation CD229/SLAMF3Biotin His Av
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS) smoldering myeloma MM and PC leukemia CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56 Most importantly CD229 was also highly expressed on those cells in the patients BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells
Sigma Aldrich Fine Chemicals Biosciences HIS SelectR Nickel Affinit
HIS-Select(R) Nickel Affinity Gel is durable and can capture the recombinant proteins with histidine tags at a high flow rate. Recombinant proteins with histidine tags are bound using either native or denaturing conditions.
AdipoGen GITRL Soluble hrecHis
Protein. The extracellular domain of human GITRL aa 74-199 is fused at the C-terminus to a His-tag. Source HEK 293 cells. Endotoxin content <0.06EU/µg purified protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in PBS. Purity >90% SDS-PAGE. GITRL Glucocorticoid-induced TNF receptor ligand is expressed on dendritic cells DC, monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues e.g. testis. GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
AdipoGen ACBP h rec His
Recombinant protein. Human acyl-CoA-binding protein aa 2-87 is fused at the C-terminus to a His-tag. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. Acyl-coenzyme A CoA-binding protein ACBP is an ubiquitously expressed 86 aa polypeptide that binds medium- and long-chain acyl-CoA esters with very high affinity. It plays a role as an intracellular carrier of acyl-CoA esters and regulates lipid metabolism in the cytoplasm of most cell types. In addition to its function within the cells as acyl-coenzyme A CoA-binding protein, ACBP also functions as secreted protein called Diazepam-Binding Inhibitor DBI that can interact with the benzodiazepine-binding site of the gamma-aminobutyric acid GABA type A receptor, GABAAR, and modulate its activity. ACBP is secreted upon induction of autophagy energy deficiency in different organisms including mouse and human. ACBP levels correlate with human body mass index BMI.
eMolecules 395101-67-4 | ChemScene | 3-Bromo-1H-indazole-5-carbonitrile | 100mg | 572175836 | CS-0042024 | MFCD09263218 | 222.045 | C8H4BrN3
Ambeed | 5-Chloro-2-hydroxyphenylboronic acid | 1g | 572830818 | A807359 | 89488-25-5 | MFCD06659863 | 172.370 | C6H6BClO3
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Genscript Corporation CD46 His Canine
CD46 was discovered in 1986 during a search for novel C3b-binding proteins CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated self-attack
Genscript Corporation MSLN/Mesothelin296-591 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally